Web16 Apr 1999 · Neurotransmitter exocytosis, a process mediated by a core complex of syntaxin, SNAP-25, and VAMP (SNAREs), is inhibited by SNARE-cleaving neurotoxins. … Web22 Sep 2000 · Synaptosomal associated protein of 25 kDa (SNAP-25) is a member of the SNARE protein complex that has been implicated in synaptic vesicle docking and fusion. In this report, we have generated SNAP-25 mutants and assayed their functions in SNARE complex formation and glutamate release from cultured rat cerebellar granule cells.
Snap25 synaptosomal-associated protein 25 [ (house mouse)]
WebSNAP-25 is a component of the SNARE complex, which is central to synaptic vesicle exocytosis, and, by directly interacting with different calcium channels subunits, it … Web1 Nov 2002 · Expression of the SNAP-25 D9 construct has been instrumental in altering the mobility of t-SNARE patches and indeed, this construct has been used to prove the function of SNAP-25, and by extension ... cdc one health antibiotic resistance
Expression and function of SNAP-25 as a universal SNARE
Web28 Nov 2024 · decreased SNAP-25 levels is the ultimate correlate of neu-rodegeneration. Our findings suggest that the neurodegen-eration in CSPa KO mice is primarily produced by defective SNAP-25 function, which causes neurodegeneration by impairing SNARE-complex assembly. The EMBO Journal (2012) 31, 829–841. doi:10.1038/ WebMolecular Function: SNAP receptor activity Source:FlyBase. 1 publication. Molecular Function: SNARE binding Source:FlyBase. 1 publication. Molecular Function: syntaxin binding Source:GO_Central. 1 publication. Biological Process: ... PF00835 SNAP-25 1 hit; SMART. View protein in SMART; SM00397 t_SNARE 2 hits; Web27 Sep 2024 · Besides its crucial role in developmental disorders, SNAP-25 is involved in aging-related disorders such as Alzheimer’s disease. For example, both SNAP-25 SNPs … cdc on ddt