Phzf family phenazine biosynthesis protein
Webb24 juli 2024 · Phenazine biosynthesis protein PhzF (E.C. 5.3.3.17) is an example of an enzyme that catalyzes an unusual reaction for which substantially different mechanistic … Webb(GenBank) PhzF family phenazine biosynthesis protein. Organism: pano Pantoea anthophila. SSDB: Ortholog Paralog Gene cluster GFIT: Motif: Pfam: PhzC-PhzF Pro_racemase: Motif: Other DBs: NCBI-ProteinID: UZH03227: LinkDB: All DBs: Position: complement(228125..228973) Genome browser: AA seq: 282 aa AA seq DB search
Phzf family phenazine biosynthesis protein
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WebbInvolved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA). Pfam Domain Function. Webb21 mars 2024 · PBLD (Phenazine Biosynthesis Like Protein Domain Containing) is a Protein Coding gene. Diseases associated with PBLD include Retinal Arteries, Tortuosity …
WebbFig. 3. 1H-NMR spectra of DHHA and PhzF in H2O (A) or 2H2O (B) 5 min after addition of the enzyme. Resonances of DHHA have been crossed. The assignment of the first product of PhzF is indicated. Strong peaks not belonging to this product are highlighted in gray, and methylene resonances are shown in a black box. Note that the proton at C1 is present in … Webb12 aug. 2004 · PhzG is a flavin-dependent oxidase that is believed to play a role in phenazine antibiotic synthesis in various bacteria, including Pseudomonas. Phenazines are chorismic acid derivatives that provide the producing organisms, including the opportunistic pathogen P. aeruginosa, with a competitive growth advantage.
WebbPublications of the research group structure and functions of Proteins(SFPR) View Item; JavaScript is disabled for your browser. Some features of this site may not work without it. Browse. ... Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF. WebbOne of the important and necessary practices for improving nutrients availability in sustainable agriculture is using microorganisms. Beside the negative effects of chemical fertilizers on the soil and human health, plant growth promoting rhizobacteria are known as an alternative to supply the organic nutrients of plants during the past two decades.
WebbPhzA, -B, and -G have no activity toward DHHA. However, in the presence of PhzF, individually or in combinations, they accelerate the formation of PCA from DHHA and …
WebbGenome analyses and comparisons of phylogenies inferred from sequences of the key phenazine biosynthesis (phzF) and housekeeping (rrs, recA, rpoB, atpD, and gyrB) genes … orions hus horsensWebbdetailed structural and biochemical analyses of PhzF, its substrate, and its products, and we propose a catalytic mechanism for the condensation of DHHA to PCA. PhzF exhibits … how to write hello in different languagesWebbPhzF catalyzes a key reaction in their biosynthesis by isomerizing (2 S,3 S)-2,3-dihydro-3-hydroxy anthranilate (DHHA) in two steps, a [1,5]-hydrogen shift followed by … how to write hello in dutchWebbPhenazine Biosynthesis Protein PhzF Christina Diederich1,5, Mario Leypold2, Martin Culka 3, Hansjörg Weber2, Rolf Breinbauer 2, G. Matthias Ullmann 3 & Wulf Blankenfeldt 1,4,5 how to write hello everyoneWebb15 nov. 2004 · PhzF exhibits significant structural similarity to members of the diaminopimelate epimerase (DapF) fold family of proteins, but differences in key active … orion sightWebb15 nov. 2004 · PhzF is a dimer that may be bifunctional, providing a shielded cavity for ketone dimerization via double Schiff-base formation to produce the phenazine scaffold. Our proposed mechanism is supported by mass and NMR spectroscopy. The results are discussed in the context of related structures and protein sequences of unknown … how to write hello in arabicWebb(GenBank) PhzF family phenazine biosynthesis protein. KO: K06998 : trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC:5.3.3.17] Organism: dnp Devosia neptuniae. Pathway: ... 00405 Phenazine biosynthesis N8A98_16485 09140 Cellular Processes 09145 Cellular community - prokaryotes 02024 Quorum sensing how to write hello in hindi