Phospho s727
WebProperties. Description. Rabbit Monoclonal Antibody to STAT3 (phospho S727) Background. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. WebHere, we studied the role of STAT3 activation on tyrosine 705 (Y705) and serine 727 (S727) in glioma radioresistance. This study explored STAT3 phosphorylation on Y705 (pSTAT3-Y705) and S727 (pSTAT3-S727) in glioma cell lines and in clinical samples. Radiosensitizing effect of STAT3 activation down-modulation by Gö6976 was explored.
Phospho s727
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WebCitations: (293) The Phospho-Stat3 (Ser727) Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody to STAT3. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-Stat3 (Ser727) Antibody has been validated for the following applications: Precipitation, ChIP, Immunoprecipitation, and Western Blot. WebMay 4, 2024 · Serine kinases play a more nuanced role in regulating Stat3 due to direct Stat3 activation through S727 phosphorylation ( 16) by kinases such as mTOR ( 7) and others, which also have the potential for competing inhibitory effects from parallel downregulation of Stat3 tyrosine phosphorylation pathways ( 17 ).
WebNov 13, 2024 · Phospho-S727 Stat3 localizes in mitochondria Recently, Larner and Levy groups described that phospho-Stat3 S727, but not phospho-Stat3 Y705, led to the accumulation of Stat3 in the... WebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA RayBiotech The store will not work correctly in the case when cookies are disabled. JavaScript seems to be disabled in …
WebSynthetic peptide within Human STAT1 (phospho S727). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Database link: P42224 WebA phospho specific peptide corresponding to residues surrounding Serine 727 of human Stat-1 was used as an immunogen. This antibody only …
WebMar 23, 2024 · Phospho-STAT1 (Ser727) and Total STAT1 ELISA Kit Catalog #: PEL-Stat1-S727-T User Manual Last revised March 23, 2024 Caution: Extraordinarily useful information enclosed ISO 13485 Certified 3607 Parkway Lane, Suite 100 Norcross, GA 30092 Tel: 1-888-494-8555 (Toll Free) or 770-729-2992, Fax:770-206-2393 Web: www.RayBiotech.com, …
WebApr 23, 2002 · Phosphorylation of S727 in Stat1 can be induced by a variety of stimuli such as IFN-γ, lipopolysaccharide, and UV, and p38 mitogen-activated protein (MAP) kinase has been implicated in lipopolysaccharide- or UV-induced phosphorylation of S727 in Stat1 ( … tachometer gauge aviationWebWestern blot - Phospho-STAT3-S727 Rabbit pAb (AP0474) Western blot analysis of extracts of various cell lines, using Phospho-STAT3-S727 antibody (AP0474) at 1:1000 dilution.HepG2 cells and C6 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.HepG2 cells were treated by CIP (20uL/400ul) at 37℃ for ... tachometer generator motorWebUsing a combination of HepG2-stat3-knockdown cells reconstituted with various STAT3 mutants and protein kinase inhibitors, we showed that phospho-S727 has an intrinsic … tachometer graingertachometer h7cxWebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727 in Western blots. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human STAT3 S727 site Accession # P40763 Formulation tachometer hargaWebPhospho-Stat1 (Ser727) Antibody detects endogenous levels of Stat1α only when phosphorylated at Ser727. This site is deleted in Stat1β. This antibody does not … tachometer graphicWebMay 25, 2000 · The critical importance of S727 phosphorylation for the biological impact of IFN-γ is further supported by studies with mediators of inflammation (LPS, TNF-α), which cooperate with IFN-γ in the... tachometer glass replacement