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Lamp2

TīmeklisLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate … TīmeklisLAMP2蛋白；溶酶体关联膜蛋白2 (LAMP2)重组蛋白长期储存，建议添加载体蛋白（0.1％HSA或BSA），并储存在-20~ -80°C。. 避免多次冻融。. 影响蛋白原核表达的因素很多，如蛋白的亲水性、密码子的稀有性、蛋白毒性等。. 如疏水性过强，就难以表达；稀有密码子过多或 ...

Characterisation of Lamp2-deficient rats for potential new

TīmeklisFigure 1 The expression of PHLPP in bortezomib-resistant MM cells. (A) Western blot analyses of the expression of PHLPP, LAMP2, and key autophagy signaling molecules in bone marrow samples from patients with MM (upper), and quantification of the bands (lower).(B) Western blot analyses of the expression of PHLPP, LAMP2, and key … Tīmeklis2024. gada 27. sept. · LAMP-2 Antibody (H4B4) is an IgG 1 κ mouse monoclonal LAMP-2 antibody (also designated LAMP2 antibody, LAMPB antibody or lysosomal associated membrane protein 2 … phillippi shores elementary https://davemaller.com

Anti-LAMP2 antibody produced in rabbit - Sigma-Aldrich

Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This … Skatīt vairāk The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C … Skatīt vairāk Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the … Skatīt vairāk • CA77.1 • QX39 Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. PMID 12144129. • Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L, … Skatīt vairāk LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous tumors, specifically in cells of highly … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information … Skatīt vairāk TīmeklisLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate … Tīmeklis2024. gada 7. nov. · LAMP2 was preferentially expressed by RPE cells, and its expression declined with age. Deletion of the Lamp2 gene in mice resulted in age … phillippi shores elementary school ixl

PHLPP Sensitizes Multiple Myeloma Cells to Bortezomib Through ...

Category:Chronic acidosis in the tumour microenvironment selects for ...

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Lamp2

Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and …

TīmeklisThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the … Tīmeklis2024. gada 7. febr. · Lysosomal membrane-associated protein 2 (Lamp2) is an important component of lysosomal membranes and is involved in both autophagy and LMP. In the present study, we found …

Lamp2

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TīmeklisMoreover, LAMP2 deficiency also leads to the loss of lysosomal membrane integrity, resulting in reduced retention of cathepsin D within the lumen . Given the intimate relationship between LAMP2 and cathepsin D, we determined the effect of HQ on cathepsin D protein expression in RPE cells. TīmeklisLAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation. LAMP2 deficiency causes an accumulation of …

TīmeklisLAMP2 mutations are associated with striking evidence of LVH. A. An electrocardiogram demonstrates a short PR interval, delta waves, and prominent voltage (R waves … Tīmeklis2024. gada 10. maijs · LAMP2 is dispensable for the establishment of major TEC microenvironments. To identify new candidates involved in the antigen processing capacity of cTECs, we analyzed our transcriptomic data from postnatal cTECs and mTECs [Citation 14], together with available data sets from other studies [Citation 15, …

TīmeklisLysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins (1,2). Both are transmembrane proteins and are heavily glycosylated at the amino … Tīmeklis2024. gada 1. janv. · LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, …

Tīmeklis2024. gada 25. aug. · LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, …

TīmeklisLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate … phillippi shores apartmentsTīmeklis2015. gada 10. dec. · The protein LAMP2 functions to protect lysosomal membranes from acid proteolysis. In this study, the authors show that malignant cells adapt to the acidic tumour microenvironment by redirecting ... phillippi shores elementary sarasotaTīmeklisLAMP2 (lysosome-associated membrane protein 2) is a heavily glycosylated intrinsic protein (110kD) present in lysosomal membrane. The protein glycosylation is essential for its function to protect the lysosomal membrane from proteolytic enzymes. Anti-LAMP2 antibody can be used in western blotting. It can also be used as a lysosomal … tryshia centenoTīmeklis2024. gada 8. janv. · Lysosome-associated membrane protein-2 (LAMP2), is a highly glycosylated lysosomal membrane protein involved in chaperone mediated autophagy. Mutations of LAMP2 cause the classic triad of myopathy, cardiomyopathy and encephalopathy of Danon disease (DD). Additionally, retinopathy has also been … phillip pippengerTīmeklis2024. gada 7. nov. · Lamp2 knockout (KO) mice are characterized by disrupted autophagy and phagocytosis in hepatocytes, neurons, and leukocytes (23–26). Loss-of-function mutations of the human LAMP2 gene cause Danon disease, a lysosomal storage disorder characterized by cardiomyopathy, skeletal myopathy, and mental … trysher pruning servicesTīmeklis2024. gada 18. marts · LAMP2 has three isoforms: LAMP2A, LAMP2B, and LAMP2C. LAMP2B is the predominant isoform expressed in cardiomyocytes. This study evaluates the efficacy of human LAMP2B gene transfer using a recombinant adeno-associated virus 9 carrying human LAMP2B (AAV9.LAMP2B) in a Lamp2 knockout (KO) mouse, … phillippi shores elementary shelterTīmeklis2024. gada 29. dec. · LAMP2 is a lysosomal membrane protein that plays a key role in the maturation of lysosomes and their fusion with autophagic vacuoles [ 4, 5 ]. Thus, … phillippi shores facebook