WebJan 16, 2024 · Background The genome-wide association study has founded hypertension-related single nucleotide polymorphism (SNP) rs11191548 near CYP17A1 encoding a key enzyme involved in steroid metabolism, but the molecular mechanisms are not understood and the associations of the SNP with hypertension-related traits are not fully described, … WebDescription. Hypertension is abnormally high blood pressure in the arteries, which are the blood vessels that carry blood from the heart to the rest of the body. As the heart beats, it forces blood through the arteries to deliver nutrients and oxygen to the rest of the body. The strength of the blood pushing against the artery walls is blood ...
The genetics of blood pressure - National Institutes of Health (NIH)
WebAug 3, 2024 · Blood pressure and hypertension are polygenic traits. Genome-wide association studies have identified over 900 SNPs associated with blood pressure that … WebJul 1, 2024 · Genetic architecture of blood pressure and hypertension To successfully map the genetic basis of a trait, a good understanding of the genetic architecture of the trait is required. The genetic architecture of a trait refers to the number of disease variants that exist, their allele frequencies, the risks that they confer, and the interactions ... parts for woods 3180 bush hog
Genomics of hypertension: the road to precision medicine
WebMay 18, 2024 · The pathogenesis of essential hypertension is multifactorial and highly complex. The kidney is both the contributing and the target organ of the hypertensive processes, [] and the disease involves the interaction of multiple organ systems and numerous mechanisms of independent or interdependent pathways. Factors that play an … WebThe genetics of hypertension are quite complex since it involves multiple genes with only mild effects on phenotype, gene–gene interactions (epistasis), and genes that manifest … WebOct 6, 2024 · Introduction. Hypertension (HT) has been the most common public-health cardiovascular disease with a high incidence and a range of changeable and complex complications worldwide ().Moreover, HT is a complex systemic disease, which not only endangers the cardiovascular system, but also damages other organs and systems … timtam power massager vs theragun