Cst foxo3a

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August undefined, 2024

WebApr 11, 2024 · Nutrition during the developmental stages has long-term effects on adult physiology, disease and lifespan, and is termed nutritional programming. However, the underlying molecular mechanisms of nutritional programming are not yet well understood. In this study, we showed that developmental diets could regulate the lifespan of adult … WebHighly specific and rigorously validated in-house, FoxO3a Antibody (CST #9467) is ready to ship. ... Within the family, three members (FoxO1, …

FoxO3a (75D8) Rabbit mAb Cell Signaling Technology

Web(12829) FoxO3a (D19A7) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary Clonality Recombinant (D19A7F3) Recombinant Yes Conjugate Unconjugated Target Forkhead box protein O3 (Human) UniProt O43524 - FOXO3_HUMAN Gene FOXO3 Modification … WebMar 27, 2008 · A number of posttranslational modifications within the forkhead DNA-binding domain regulate FoxO-mediated transcription. We describe the crystal structures of … theoretische brille

Proteolytic regulation of Forkhead transcription factor FOXO3a

WebForkhead box O (FOXO) proteins are a family of transcription factors with four members in mammals, namely FOXO1, FOXO3a, FOXO4, and FOXO6. FOXO factors, originally … WebFoxO3a (75D8) Rabbit mAb detects exogenous and endogenous levels of total FoxO3a protein. The antibody does not detect the exogenously expressed family members FoxO4 or FoxO1. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification WebFeb 18, 2024 · Previous evidence showed that the SIRT3–FOXO3a axis was a tumor suppressor in many cancers 42-44 it influenced EMT, 45 proliferation 46 and apoptosis. 47 Here, we confirmed that Adjudin activated the SIRT3–FOXO3a axis in SCLC, and the anticancer effect of Adjudin can be influenced by the expression levels of SIRT3 and … theoretische chemie skript

Human endometrial mesenchymal stem cells exhibit intrinsic

Dietary isoleucine improved flesh quality, muscle antioxidant …

WebApr 22, 2024 · FOXO3a is a key target of AKT, and AKT phosphorylates FOXO3a at Thr32 residues, resulting in a decreased expression of FOXO3a. We then investigated whether … WebThe FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell proliferation, differentiation, cell survival, senescence, DNA … theoretische chemie jobsWeb丁香通为您提供C2810MG商品详情介绍：价格：￥500，货号：7546/10，CAS号：详询，品牌：Tocris，产地：英国，供应商：北京百奥 ... theoretische chemie pdf

"WebJan 1, 2012 · Doxorubicn treatment induces p38 MAPK activity and FOXO3a nuclear accumulation in MCF-7 breast carcinoma cell line. A, MCF-7 cells were treated with 1 μmol/liter of doxorubicin for 0, 1, 2, 4, 8, 16, and 24 h. At the indicated time, the cells were collected and analyzed by Western blotting using the antibodies indicated. " - Cst foxo3a

Cst foxo3a

3COA: Crystal Structure of FoxO1 DBD Bound to IRE DNA - RCSB

WebNov 15, 2016 · Besides, FoxO3a can trigger apoptosis by promoting the expressions of death receptor ligands in the extrinsic apoptotic pathway, such as Fas ligand 33 and tumor-necrosis-factor-related apoptosis ... WebJul 16, 2024 · The differential expressions of IGF-1R, FOXO3A, and BIM in the benign versus malignant prostate tissues supported a negative association between the FOXO3A/BIM axis and IGF-1R expression in human ...

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Web56484 Ensembl ENSG00000118689 ENSMUSG00000048756 UniProt O43524 Q9WVH4 RefSeq (mRNA) NM_001455 NM_201559 NM_019740 NM_001376967 RefSeq (protein) NP_001446 NP_963853 NP_062714 NP_001363896 Location (UCSC) Chr 6: 108.56 – 108.68 Mb Chr 10: 42.06 – 42.15 Mb PubMed search Wikidata View/Edit Human … WebIOP1抗体、Lamin A/C抗体、LC3BⅠ抗体、LC3BⅡ抗体、FOXO3a抗体、p62抗体、ATG5、ATG12抗体、GAPDH抗体均购自美国CST公司。荧光定量PCR仪型号为LightCycler 480，购自瑞士罗氏公司。 1.2方法. 1.2.1细胞培养 HEK293T在37 ℃，5% CO2培养箱中用含10% FBS的高糖DMEM培养基培养。

WebMonoclonal Antibody for studying FoxO3a. Cited in 187 publications. Validated for WB, IP, IHC, IF, F. Highly specific and rigorously validated in-house, FoxO3a (D19A7) Rabbit Monoclonal Antibody (CST #12829) is …

WebMonoclonal Antibody for studying FoxO3a. Cited in 455 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in … WebForkhead box O (FOXO) proteins are a family of transcription factors with four members in mammals, namely FOXO1, FOXO3a, FOXO4, and FOXO6. FOXO factors, originally identified as downstream regulators of the insulin pathway, are known to bind to the promoters of a broad variety of target genes and co … Introduction to FOXO Biology

Gopinath et al. (2014) demonstrate a functional requirement for FOXO3 as a regulator of Notch signaling pathway (an essential regulator of quiescence in adult stem cells) in the self-renewal of stem cells during muscle regeneration. It is thought that FOXO3a is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD. Ron DePinho's group generated Foxo3 knockout mic…

WebApr 19, 2024 · The primary antibodies used in this study were AKT (1:1000; total and Ser473, Cell Signaling Technology Inc., Danvers, MA, USA), TOR (1:2000; total and Ser2448, CST), S6K1 (1:2000; total and Thr421/Ser424, CST), FOXO3a (1:3000; total and Ser253, Abcam, Cambridge, MA, USA), MAFBX and MURF-1 (1:4000; Zen … theoretische concepten reflectieWebNov 1, 2024 · Results. Exercise can significantly attenuate AngⅡ-induced muscle atrophy, which is demonstrated by increased skeletal muscle weight, cross-sectional area of myofiber, and activation of AKT/mTOR signaling and by decreased atrogenes expressions and apoptosis. In AngⅡ-induced muscle atrophy mice models, PPARγ was elevated … theoretische concepten zorgWebFOXO3a is a transcription factor of the FOXO family. The FOXO proteins participate in multiple signaling pathways, and their transcriptional activity is regulated by several post … theoretische criminologie probleem 7WebMar 1, 2024 · Chitosan targets PI3K/Akt/FoxO3a axis to up-regulate FAM172A and suppress MAPK/ERK pathway to exert anti-tumor effect in osteosarcoma - ScienceDirect Chemico-Biological Interactions Available online 25 January 2024, 110354 In Press, Journal Pre-proof Research paper theoretische criminologieWebJun 28, 2024 · The following primary antibodies were used: Ubiquitin (#3933; Cell Signaling Technology (CST) Japan, Tokyo, Japan), p-Forkhead box O (FOXO) 1 Ser256 (#84192; CST), FOXO1 (#2880; CST), p-FOXO3a Ser253 (#9466; CST), FOXO3a (#2497; CST), LC3 (#2775; CST), p62/SQSTM (PM045, Medical & Biological Laboratory, Nagoya, Japan), p … theoretische diskussionWeb人远端上游元件结合蛋白1(fubp1)elisa试剂盒；英文名称： fubp1 elisa kit ；实验名称：人远端上游元件结合蛋白1(fubp1)elisa试剂盒；实验别名：人远端上游元件结合蛋白1(fubp1)elisa试剂盒 48t/96t ；规格： 48t/96t 报价人远端上游元件结合蛋白1(fubp1)elisa试剂盒实验目的：本试剂盒仅供研究使用，用于用于 ... theoretische contextWebFeb 14, 2024 · The transcription factor FoxO3A is a key determinant of cancer cell homeostasis, playing a dual role in survival/death response to metabolic stress and cancer therapeutics. We recently described a novel mitochondrial arm of the AMPK-FoxO3A axis in normal cells upon nutrient shortage. theoretische durchdringung definition